Japanese scientists form world’s first jawbone using human-iPS cells
(MENAFN) Researchers in Japan have successfully created the world’s first 3D jawbone-like organoids using human-induced pluripotent stem (iPS) cells, according to reports.
When transplanted into mice, these organoids matured into fully developed bone tissue, demonstrating the potential of the approach. The research team from Kyoto University believes that their method could have significant applications in regenerative medicine and drug discovery.
The study’s results were published in the July online edition of Nature Biomedical Engineering.
Creating a jawbone has long been considered a challenge because its developmental process differs from that of other bones, and replicating the intricate network of jawbone cells was previously not feasible. In this study, researchers collected and cultured human iPS cells to form cell aggregates, which then differentiated into jawbone cells.
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