Japanese Scientists Achieve 3D Jawbone-Like Organoids
(MENAFN) In a significant scientific advancement, Japanese scientists have successfully produced the world’s first 3D jawbone-like organoids using human-induced pluripotent stem (iPS) cells, according to a news agency on Tuesday.
Once implanted into mice, these tiny organoids matured into fully developed bone tissue, signaling a promising step forward in the field of regenerative therapies.
The researchers, based at Kyoto University, anticipate that the approach demonstrated in their study could be used for regenerative treatments and pharmaceutical testing in the future.
Details of their research were shared in a digital issue of the global journal Nature Biomedical Engineering in July.
Generating a jawbone posed a unique challenge because its formation process is distinct from that of other bones in the human body.
Furthermore, there had previously been no adequate technology capable of mimicking the intricate network of bone cells that form the majority of the jawbone structure.
To overcome these obstacles, the scientists cultivated human iPS cells, encouraging them to form clusters of cells that would later differentiate into jawbone cells.
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